If you expect the best of the best, enjoy outstanding service and experience luxury like no other in DeSoto 5-star properties. Find the best deals and unwind in style at iconic five star hotels in DeSoto. These world class DeSoto hotels offer luxurious accommodations with premium locations. Check out this list of DeSoto ultra-opulent hotels to pamper yourself. From modern to classic the DeSoto area hotels offer something for your specific liking.